Calculating RBSL (RBEL)

• Using the intake equation and setting the target risk or hazard quotient, solve for the concentration

• The resulting concentration is the RBSL or RBEL

• Correct slope factor for carcinogens

  • oral (ingestion)
  • dermal (dermal contact)
  • inhalation unit risk factor (inhalation) or inhalation slope factor

• Correct reference doses for non-carcinogens

  • oral (ingestion)
  • dermal (dermal contact)
  • reference concentration (inhalation) or inhalation reference dose

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Inhalation unit risk value already accounts for the inhalation rate

The inhalation reference dose was commonly used until recently; reference concentrations are also being used now. They account for the inhalation rate as well.