Toxicity Assessment

• Sources of Toxicity Information (by preference)

  • State specific toxicity values
  • IRIS - Integrated Risk Information System
    • contains only RfDs and slope factors reviewed by EPA.
    • no external peer review of safe dose estimates (RfDs, SFs).
  • EPA Criteria Documents
  • HEAST - Health Effects Assessment Summary Tables
    • summarizes all toxicity data.
    • no internal or external peer review of quality of data.
  • ATSDR - Agency for Toxic Substances and Disease Registry
  • peer-reviewed literature

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